ROLE OF THE REGULATOR OF G PROTEIN SIGNALING RGS9 IN PANCREATIC ISLET FUNCTION Our laboratory is studying pancreatic islet biology using ex vivo systems and preclinical models. More specifically, a significant portion of our research programs aims to decipher the function and mechanisms of action of G protein-coupled receptors and their regulatory proteins in islets …
Congratulations to Alexis Vivoli whose article entitled ‘Single-cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty-Acid-Induced Rat Beta-Cell Proliferation’ was published in the journal Diabetes.
Congratulations to Anne-Laure Castell and Clara Goubault whose article entitled ‘Beta-cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood’ was published in the journal JCI Insight.
Click here to access these protocols: Measurement of pancreatic islet beta-cell proliferation by flow cytometry dx.doi.org/10.17504/protocols.io.n92ldz8d9v5b/v1 Immunofluorescent staining of pancreatic sections dx.doi.org/10.17504/protocols.io.bg6ujzew Preparation of BSA complexed free fatty acids for in vitro studies dx.doi.org/10.17504/protocols.io.b6r2rd8e RNA in situ hybridization on pancreatic sections using RNAscope® technology dx.doi.org/10.17504/protocols.io.e6nvw9367gmk/v1
Dr. Poitout was invited to discuss why obesity during puberty leads to a higher risk of Type 2 diabetes. Listen to the podcast here: Diabetes 360: Season 7, Episode 4.
Congratulations to Anne-Laure Castell and Alexis Vivoli whose article entitled ‘Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation’ was published in the journal Diabetes.
Congratulations to Hasna Maachi whose article entitled ‘Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans’ was published in the journal Scientific Reports.
Congratulations to Anne-Laure Castell who was awarded an ‘Allocation jeune chercheur clinicien’ from the Société Francophone du Diabète (SFD) for her project entitled: Role of kisspeptin in the control of beta-cell proliferation during puberty.
Congratulations to Vincent Poitout who received the ‘Prix des fondateurs Jean-Davignon et Paul-Lupien’ 2021 de la SQLNM’ at the virtual SQLNM/CMDO/COLosSUS meeting held in February, 2021.
Congratulations to Alexis Vivoli who was awarded a prize for best poster presentation at the virtual SQLNM/CMDO/COLosSUS meeting held in February, 2021.
