POITOUT LABORATORY
Canada Research Chair in Diabetes and Pancreatic ß-cell Function

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June 2017 -- Congratulations to Dr. Anne-Laure Castell who was awarded a research prize from La Société française d'endocrinologie pédiatrique and Novonordisk for her project "Role of growth hormone in adaptive pancreatic β-cell function in the face of pubertal insulin resistance".

June 2017 -- Dr. Marine Croze received a Post-doctoral Fellowship Award from the Montreal Diabetes Research Center (MDRC).

May 2017 -- Congratulations to Valérie Bergeron who won a prize for best abstract presentation during the 2017 CRCHUM Student Congress.

February 2017 -- Congratulations to Hasna Maachi and Valentine Moullé who won a prize for best oral presentation during the SQLNM/CMDO/COLosSUS 2017 Congress in Magog Québec.

January 2017 -- Dr. Valentine Moullé's article " Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats" is [Epub ahead of print] in Diabetologia, 2017, doi: 10.1007/s00125-016-4197-8. View article.

December 2016 -- As part of Diabetes Awareness Month, view Dr. Vincent Poitout's interview on LCN.

October 2016 -- Valérie Bergeron article " The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1" is [Epub ahead of print] in Islets, 2016, DOI: 10.1080/19382014.2016.1243191. View abstract in PubMed.

October 2016 -- View Dr. Vincent Poitout and Kevin Vivot talk about RGS16 as a novel regulator of beta cell function in Molecular Metabolism.

September 2016 -- Congratulations to Kevin Vivot who participated in the Montreal Marathon with a time of 3:14. He finished 140th of 4545 participants.

August 2016 -- Kevin Vivot article " The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets" is published in Molecular Metabolism, 2016, 5(10): 988-996.

August 2016 -- Laetitia Koppe article " Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease" is [Epub ahead of print] in J Clin Invest, 2016, pii: 86181. doi: 10.1172/JCI86181. View abstract in PubMed.

April 2016 -- On Sunday April 24th, the Poitout lab members took part in the 2016 Banque Scotia Charity Challenge to raise funds for the research done at the CRCHUM. Congratulations to all participants!

March 2016 -- Julien Ghislain and Ghislaine Fontés article " Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry" is published in Endocrinology, 2016, 157(3): 1299-306. View abstract in PubMed.

February 2016 -- Congratulations to Hasna Maachi for her prize of the best poster at the 10th Annual MDRC Retreat in Montréal, Qc.

February 2016 -- Congratulations to Dr. Kevin Vivot for his prize of the Elite poster at the 2016 SQLNM, CMDO, COLosSUS annual Congress, in Magog, Qc.

February 2016 -- Stéphanie Auguste's article " Central agonism of GPR120 acutely inhibits food intake and food reward and chronically suppresses anxiety-like behaviour in mice" is published in International Journal of Neuropsychopharmacology [epub ahead of print]. View abstract in PubMed.

September 2015 -- Dr. Vincent Poitout was appointed Director of Research at the Centre Hospitalier de l'Université de Montréal (CHUM) and Scientific Director of the CHUM Research Center (CRCHUM) . View the article on the CRCHUM Web site.

September 2015 -- Dr. Ghislaine Fontés's article " The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator is Associated with Progressive Insulin Resistance and Decreased Functional Beta-Cell Mass in Mice" is published in Diabetes [epub ahead of print]. View abstract in PubMed.

July 2015 -- Dr. Arturo Mancini's article " ß-arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1" is published in J Biol Chem 2015 290(34):21131-40. View abstract in PubMed.

June 2015 -- Dr. Kevin Vivot received a travel award from the Montreal Diabetes Research Center (MDRC).

May 2015 -- Valérie Bergeron, PhD Student, received the Défi-CRCHUM 2014-2015 travel award.

May 2015 -- Congratulations to Elsa Nyam for her Novartis 2015 travel award for the best oral presentation by an MSc student at Simon-Pierre Noël research day at the Biochemistry Department of the Université de Montréal, May 6th 2015.

April 2015 -- On Sunday April 26th, the Poitout lab members took part in the 2015 Banque Scotia Charity Challenge to raise funds for the research done at the CRCHUM. Congratulations to all participants!

February 2015 -- Congratulations to Dr. Laetitia Koppe for her prize of best poster presentation at the SQLNM/CMDO/COLosSUS Congress, February 18 to 20,2015.

February 2015 -- Congratulations to Dr. Laetitia Koppe for her prize of best poster presentation at the 9th MDRC Annual Retreat, February 6th 2015.

December 2014 -- Congratulations to Dr. Laetitia Koppe for her prize of best poster presentation as a Post-doc Fellow at the 17th CRCHUM Student Congress, December 5th 2014.

November 2014 -- Elsa Nyam, MSc student, received a BCM-FESP Scholarship Award from the Université de Montréal.

October 2014 -- Dr. Meriem Semache's article "Pancreatic and Duodenal Homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cells" will be published in Islet.

September 2014 -- Dr. Laetitia Koppe received a Post-doctoral Fellowship Award from the Grand labo CRCHUM.

July 2014 -- Dr. Laetitia Koppe received a Post-doctoral Fellowship Award from the Fonds de recherche Québec, Santé (FRQS).

June 2014 -- Dr. Vincent Poitout was appointed the interim Director of research, CRCHUM.

June 2014 -- Dr. Kevin Vivot received a Travel Award from the Montreal Diabetes Research Center (MDRC).

May 2014 -- Congratulations to Meriem Semache who was awarded her PhD degree on May 5th.

May 2014 -- Leticia Angulo, PhD student at the École de Technologie Supérieure and co-directed by Dr. Vincent Poitout, received a Studentship Award from the Fonds de recherche Québec, Nature et Technologie (FRQNT).

May 2014 -- Hasna Maachi, PhD student, received a Studentship Award from the Fonds de recherche Québec, Santé (FRQS).

May 2014 -- Dr. Kevin Vivot received a Post-doctoral Fellowship Award from the Fonds de recherche Québec, Santé (FRQS).

February 2014 -- Congratulations to Dr. Arturo Mancini for his prize of best oral presentation at the SQLNM-COLosSUS Congress, February 19th 2014 in Quebec City.

January 2014 -- Drs. Arturo Mancini and Vincent Poitout's article "The fatty-acid receptor FFA1/GPR40 a decade later" was selected in the Top 10 Reviews of 2013 by the Editorial Board of TEM.

December 2013 -- Hasna Maachi, PhD Student, received a Recrutment Scholarship from Université de Montréal.

December 2013 -- Congratulations to Valérie Bergeron for her prize of best poster presentation as a PhD Student at the 16th CRCHUM Student Congress December 5th 2013.

October 2013 -- Dr. Bader Zarrouki's new article "Epidermal growth factor receptor signaling promotes pancreatic β-cell proliferation in response to nutrient excess in rats through mTOR and FOX M1" is published in Diabetes [Epub ahead of print]. View abstract in PubMed.

September 2013 -- Dr. Vincent Poitout was elected Fellow of the Canadian Academy of Health Sciences.

August 2013 -- Grace Fergusson's video and article, "A model of chronic nutrient infusion in rat", has been published on the Journal of Visualized Experiments. See the video on Jove.

July 2013 -- In a serie of videos presented on Diabète Québec's web site, Dr Poitout talks about the activities of the Montreal Diabetes Research Center and the research done by his team on the pancreatic beta-cell. See the video on Diabète Québec.

July 2013 -- Congratulations to Dr. Bader Zarrouki for his prize of best oral presentation at the 5th Islet Society Meeting held in Vancouver, Canada July 2013.

July 2013 -- Meriem Semache's article "Per-Arnt-Sim Kinase Regulates Pancreatic Duodenal Homeobox-1 Protein Stability via Phosphorylation of Glycogen Synthase Kinase 3 Beta in Pancreatic Beta Cells" is published in the Journal of Biological Chemistry 2013, 288(34): 24825-33. View abstract in PubMed.

June 2013 -- Elsa Nyam, Summer Intership student, received a scholarship from Diabete Québec.

February 2013 -- Congratulations to Meriem Semache for her prize of best oral presentation for a PhD student at the COLosSUS 5th Annual Meeting February 14th and 15th, 2013.

February 2013 -- Congratulations to Dr. Bader Zarrouki for his prize of best oral presentation for a post-doctoral fellow at the COLosSUS 5th Annual Meeting February 14th and 15th, 2013.

February 2013 -- Dr. Vincent Poitout's commentary article: "Lipotoxicity impairs incretin signalling" is published in Diabetologia 2013 Feb;56:231-233.

January 2013 -- Congratulations to Dr. Bader Zarrouki for his prize of best oral presentation at the 7th MDRC Annual Retreat January 18th.

December 2012 -- Congratulations to Dr. Bader Zarrouki for his prize of best poster by Postdoc Fellows during the 15th CRCHUM Student Congress December 18th.

November 2012 -- Dr. Vincent Poitout was appointed Chair of the National Research Council at the Canadian Diabetes Association.

November 2012 -- Dr. Vincent Poitout was appointed Adjunct Professor at McGill University, Department of Medicine, Division of Endocrinology.

July 2012 -- Dr. Mourad Ferdaoussi's article: "Free Fatty Acid Receptor 1: A New Drug Target for Type 2 Diabetes? has been published in Canadian Journal of Diabetes, Vol. 36, Issue 5, Pages 275 - 280.

July 2012 -- Dr. Mourad Ferdaoussi's article: "G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1." is published in Diabetologia 2012 Oct;55(10):2682-92.

June 2012 -- Dr. Bader Zarrouki received a travel award from the Montreal Diabetes Research Center.

June 2012 -- Dr. Arturo Mancini received a three year Postdoctoral Fellowship Award from the Canadian Diabetes Association.

April 2012 -- Dr. Julie Amyot's article: "Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Too-Like Receptor-4 and NF-kB Signalling." is published in PLoS One 2012;7(4):e36200.

February 2012 -- Congratulations to Julie Amyot who was awarded her PhD degree on February 9th.

January 2012 -- Dr. Melkam Kebede's article: "Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation." is published in Proc Natl Acad Sci USA 2012, 109(7): 2376-81.

January 2012 -- Congratulations to Dr. Melkam Kebede for her prize of best poster during the 6th MDRC Retreat last January 27th.

January 2012 -- Congratulations to Dr. Bader Zarrouki for his prize of best poster during the 6th MDRC Retreat last January 27th.

January 2012 -- Congratulations to Valérie Bergeron, PhD Student, for her prize of best poster during the 6th MDRC Retreat last January 27th.

December 2011 -- Congratulations to Dr. Melkam Kebede for her prize of best poster by Postdoc Fellows during the 14th CRCHUM Student Congress last December 13th.

December 2011 -- Congratulations to Julie Amyot for her prize of best poster by Doctorate Students during the 14th CRCHUM Student Congress last December 13th.

December 2011 -- Meriem Semache, PhD student, received an award of excellence from the University of Montreal for her PhD studies.

November 2011 -- Valérie Bergeron, PhD student, received a second scholarship from the University of Montreal for her accelerated transition from MSc to PhD studies.

September 2011 -- Vincent Poitout was appointed Scientific Director of the CRCHUM.

September 2011 -- Julie Amyot's article: "Binding of activating transcription factor 6 to the A5/Core of the rat insulin II gene promoter does not mediate its transcriptional repression." is published in J Mol Endocrinol. 2011 Sept 30;47(3):273-283.

August 2011 -- Julie Amyot, PhD student, received an award for the end of her doctoral studies from the University of Montreal.

August 2011 -- Dr. Bader Zarrouki, Postdoctoral Fellow, received a two year Research Fellowship Fund from Ely Lilly Canada.

June 2011 -- Julie Amyot, PhD student, received a travel award from the MDRC.

May 2011 -- Dr. Mourad Ferdaoussi, Postdoctoral Fellow, received a scholarship award from the Grand Labo CRCHUM.

May 2011 -- Dr. Mourad Ferdaoussi, Postdoctoral Fellow, received a travel award from the CRCHUM.

May 2011 -- Valérie Bergeron, PhD student, received a travel award from the CRCHUM.

May 2011 -- Meriem Semache, PhD student, received a two year award from the Fonds de la recherche en santé du Québec (FRSQ).

March 2011 -- Congratulations to Valérie Bergeron, PhD student, and her University of Montreal Carabin Cheerleading team who won the first Provincial Academic competition of the Réseau du sport étudiant du Québec. They are now preparing to compete at the Cheerleading World Championship in Orlando, Florida next April 28th to May 2sd.

February 2011 -- Congratulations to Meriem Semache for her prize of best poster by PhD students during the 53rd annual meeting of La Plateforme COLosSUS.

February 2011 -- Congratulations to Dr. Mourad Ferdaoussi, Postdoctoral Fellow, for his prize of best oral during the 3rd annual meeting of La Plateforme COLosSUS.

January 2011 -- Valérie Bergeron, PhD student, received a scholarship from the University of Montreal for her accelerated transition from MSc to PhD studies.

January 2011 -- Congratulations to Dr. Mourad Ferdaoussi, Postdoc Fellow, for his prize of best oral during the 5th Annual Retreat of the Montreal Diabetes Research Center

January 2011 -- Congratulations to Meriem Semache for her prize of best poster by PhD students during the 5th Annual Retreat of the Montreal Diabetes Research Center

January 2011 -- Meriem Semache, PhD student, received a scholarship from the Montreal Diabetes Research Center and the University of Montreal.

December 2010 -- Congratulations to Dr. Mourad Ferdaoussi for his prize of best poster by Postdoc Fellows during the 13th CRCHUM Student Congress last December 16th.

December 2010 -- Congratulations to Valérie Bergeron, MSc student, and her University of Montreal Carabin Cheerleading team who won the championship of the Open-Collégial-Universitaire competetion at André-Grasset College last November.

November 2010 -- Meriem Semache, PhD student, received a scholarship of excellence from the University of Montreal.

October 2010 -- Drs. Ghislaine Fontés and Bader Zarrouki's article "Glucolipotoxicity age-dependently impaired beta cell function in rats despite a marked increase in beta cell mass" is published in Diabetologia 2010, 53:2369-2379.

September 2010 -- Dr. Melkam Kebede received a Travel Award from the CHUM Research Center (CRCHUM) to attend the 13th Annual CDA/CSEM Professional Conference and Annual Meetings in Edmonton, Alberta, next October 20 to 23. 

June 2010 -- Dr. Poitout was appointed as a National Board member of the American Diabetes Association for a 3-year term starting January 1, 2011.

June 2010 -- Meriem Semache, PhD student, received a scholarship from Diabète Québec.

May 2010 -- Isma Benterki, a second year student at University of Montreal and doing a summer stage in the Poitout Lab, received a scholarship from Diabète Québec.

May 2010 -- The Poitout lab is part of a research project recently funded by the Consortium Québécois sur la décourverte du médicament (CQDM). This project is entitled "Evanescent field biosensor for label-free and real-time in situ monitoring of multiple analyses ex vivo and in vivo". This is a collaborative project headed by Dr. Emanuel Escher from Sherbrooke University. 

March 2010 -- Dr. Vincent Poitout's article: "Glucolipotoxicity of the pancreatic beta cell" is published in Biochimica et Biophysica Acta 2010 March; 1801(3): 289-298.

March 2010 -- Dr. Melkam Kebede received a Travel Award from the Montreal Diabetes Research Center (MDRC) to attend the Keystone Symposia Diabetes meeting in Whistler, British Columbia, next April 12 to 17. 

February 2010 -- Dr. Ghislaine Fontés' article: "Lack of preservation of insulin gene expression by a Glucagon-Like Peptide 1 agonist or a Dipeptidyl Peptidase 4 inhibitor in an in vivo model of glucolipotoxicity" is published in Diabetes Research and Clinical Practice 2010 March; 87(3): 322-328 .

January 2010 -- Dr. Melkam Kebede received a travel award for the Keystone Symposia Diabetes meeting in Whistler, British Columbia, next April 12 to 17. She will be presenting a poster titled: "Metabolic Regulation of GPR40 Gene Expression".

December 2009 -- Meriem Semache, PhD student, received a grant of excellence from the Biochemistry department of the University of Montreal for her study project.

October 2009 -- Dr. Melkam Kebede's article: "Lipid receptors and islet function: therapeutic implications?" is published in Diabetes, Obesity and Metabolism, 11 (Suppl. 4), 2009, 10-20.

September 2009 -- Dr Thierry Alquier's article: "Deletion of GPR40 Impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets" is published in Diabetes 2009.

August 2009 -- Dr Vincent Poitout is the 2009 recipient for the Canadian Diabetes Association, Great-West Life, London Life, and Canada Life Young Scientist Award. The award will be presented at the 2009 International Diabetes Federation World Congress to be held in Palais des Congrès, Montreal, Quebec, October 18-22, 2009.

August 2009 -- Dr Ghislaine Fontes' article: "Involvement of PAS Kinase and ERK ½ in palmitate inhibition of insulin gene expression in pancreatic beta cells" is published in Diabetes 2009 (58: 2048-2058).

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